ABSTRACT
Introducción: Piper auritum Kunth (caisimón de anís) es una de las plantas más utilizadas tradicionalmente en Cuba por sus propiedades antiinflamatorias, analgésicas y cicatrizantes. Objetivos: reportar un caso clínico que sufrió una reacción adversa por automedicación de hojas de Piper auritum. Métodos: se revisó la literatura y la historia clínica de una paciente femenina atendida en el servicio del Hospital Universitario Dr Miguel Enríquez, Servicio de Cirugía Plástica y Caumatología. Resultados: se presentó el caso de una paciente que sufrió lesiones por quemaduras hipodérmicas y sus consecuencias al aplicar hojas de P auritum de forma incorrecta sobre la piel de las mamas, que necesitaron autoinjertos de piel laminar de espesor parcial medio con resultados satisfactorios. Conclusiones: es importante la orientación por personal especializado para el uso de las plantas medicinales
Introduction: Piper aurifum Kunth (caisimón de anis) is one of the most used plants traditionally in Cuba because of its anti-inflammatory, analgesic and healing properties. Objectives: to report a clinical case suffering from an adverse reaction caused by self-medication with Piper aurifum leaves. Methods: the medical literature and the medical history of a female patient, who was seen at Dr Miguel Enríquez university hospital plastic surgery and burn treatment service, were reviewed. Results: the case of a patient who suffered lesions from hypodermic burns caused by the wrong application of P aurifum leaves on the breast skin was presented. It was necessary to use laminar skin autografts of average partial thickness to cure the lesions, with satisfactory results. Conclusions: it is important that specialists provide appropriate instructions about the use of medicinal plants
Subject(s)
Burns , Necrosis , Piper/adverse effectsABSTRACT
Cutaneous necrosis is a rare but serious complication, among patients treated with warfarin or acenocumarol derivatives. We report a 71 years old female with a history of deep venous thrombosis, receiving acenocumarol for three months. The treatment was discontinued, but had to be restarted, due to a new episode of thrombosis. Three days after restarting acenocumarol, the patient consulted for ecchymosis and pain of the right foot. At physical examination, there was distal cyanosis and absence of distal pulses. The patient was subjected to an embolectomy with the suspicion of an acute arterial occlusion, but no emboli were found. Due to the possibility of a cutaneous necrosis caused by Acenocumarol, the medication is discontinued. The cutaneous lesions progressed and eight days after the failed embolectomy, a gangrene of the right foot was diagnosed. The patient did not accept amputation dying fourteen days after the first intervention.
A propósito un caso registrado, se resume la historia clínica y se revisa la literatura, dada la escasa frecuencia de esta complicación derivada del tratamiento por anticoagulantes orales. La necrosis cutánea es un evento adverso raro, pero serio, de la anticoagulación con derivados de acenocumarol o warfarina. Se comunicó por primera vez en 1943. La incidencia de la necrosis cutánea inducida por anticoagulantes orales es de 0,01 al 0,1 por ciento de los pacientes tratados. El número de casos publicados en el mundo es de aproximadamente 300, y menos de 100 en lengua inglesa en las últimas tres décadas. Este trabajo reporta el caso de una paciente que presenta necrosis cutánea en hombro izquierdo y pierna derecha.
Subject(s)
Humans , Female , Aged , Acenocoumarol/adverse effects , Anticoagulants/adverse effects , Necrosis/chemically induced , Skin/pathology , Administration, Oral , Acenocoumarol/administration & dosage , Anticoagulants/administration & dosage , Fatal Outcome , Gangrene/chemically induced , Shoulder/pathology , Foot/pathology , Warfarin/adverse effectsABSTRACT
Aunque está bien documentada la alta incidencia de anticuerpos antifosfolípido (aPL) asociados a infección por virus de la inmunodeficiencia humana (VIH), hay pocos reportes de fenómenos trombóticos clínicos relacionados con la presencia de estos anticuerpos. Exponemos el caso de un paciente masculino de 47 años con diagnóstico reciente de infección por VIH que presentó síndrome antifosfolípido (SAF) manifestado por lesiones necróticas en piel de miembros inferiores y altos niveles de anticardiolipina IgG (aCL).
Even though it is well documented the great incidence of antiphospholipid antibodies associated with HIV infection, there are few reports of clinic thrombosis related with the presence of these antibodies. We expose the case of a 47 year old male with recent diagnosis of HIV infection, presenting with antiphospholipid syndrome manifesting as necrotic skin lesions in lower limbs and high levels of IgG anticardiolipin.
Subject(s)
Humans , Male , Middle Aged , HIV , Antiphospholipid Syndrome , Thrombosis , Antibodies, Anticardiolipin , AntibodiesABSTRACT
A case of a 4-year old Filipino female with anaphylactoid purpura complicated by cutaneous necrosis and gangrene was herein reported. Therapy with 6% Dextran infusions was dramatic and rewarding as evidenced by cessation of further progression of the ischemic lesions and the eventual drying up of almost all cutaneous manifestations. Mention was made of the extreme rarity of the present case as attested by only a few cases so far reported in the literature. (Summary)